The MSToolkit library for clinical trial design

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Documentation for package ‘MSToolkit’ version 3.2.3

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MSToolkit-package Generates and analyzes simulated trial data
addResidualError Add residual error to the response.
allocateTreatments Allocate treatment to subjects
analyzeData Analyze simulated data replicates
analyzeRep Analyse a single replicate of data
applyPredCode Parses and applys NONMEM statements
calculateDiffsFromBase Calculate differences from baseline
calculateObsSummary Calculate Observed Data Summary
calculateSimTrialMeans Calculate Simulated Trial Means
checkColNames Parse alpha value
checkDropOutFun check the user supplied drop out function
checkMacroFormat check the macro format dataset
checkMicroFormat Check that an input data structure is a valid "Micro Evaluation" structure
checkSimAlpha Parse alpha value
checkSymmetricPDMatrix Checks if a matrix is symmetric and positive definite
compileSummary Compile all Micro or Macro evaluation data
convertSASIncludeRows Create a SAS 'IF' statement
convertToSASCode Convert R to SAS Statements
createContinuousCovariates Create a set of continuous covariates
createCovariates Create covariates
createDirectories Create replicate data, micro evaluation, and macro evaluation directories
createDiscreteCovariates Create covariates from a discrete distribution
createDropout Adds dropout to a simulated dataset
createEmptyMicro Create an empty micro evaluation data frame
createExternalCovariates Create covariates by sampling from an external file
createExternalParameters Sample parameters from an external file
createInterims create the interim flag
createMCAR Missing Completely at Random
createNmMatrix Creates a matrix based on a "NONMEM style" vector
createNmParSamples Simulate parameter sets from a NONMEM run object
createNormalParameters Create parameters based on a multivariate normal distribution
createParameters Create parameter data for subjects in a simulated trial
createResponse High-level function for the response component.
createResponseVariable Create a response from a data set and an equation
createTimeVaryingCovariates Create a set of time-varying covariates
createTreatments Create Treatment Design Data
createTvDefinition Create "Typical Value" Definition
ectdStop Error handling functions for the ectd package.
ectdWarning Error handling functions for the ectd package.
generateData Generate simulated data replicates
getEctdColName Control of default column names
getEctdDataMethod Current data storage method
getEctdDateFormat MSToolkit package options
getEctdExternalPath Controls paths to a set of external execution paths
getEctdLogFile MSToolkit package options
getEctdPossibleColNames Control of default column names
getEctdVerbose MSToolkit package options
getReplicates Trial replicates vector
initialChar Convert the first letter that occurs in a string to lower case
interimAnalysis interim Analysis
macroEvaluation Macro Evaluation
matchEctdColNames Control of default column names
MSToolkit Generates and analyzes simulated trial data
mstoolkitUnitTests Unit/System Tests suite for the MSToolkit package
parseCharInput Parse a comma seperated string
parseCovMatrix Parse a covariance matrix
parseHashString Process a string seperated by hash symbols or a vector (or list) of strings not containing any hash symbols
parsePredCode Parses and applys NONMEM statements
parseRangeCode Parse a numerical range expression
parseRCode Parse R Code
performAnalysis Runs the analysis code against one dataset
readAllData Read scenario data
readData Read scenario data
removeDirectories Remove directories
resetEctdColNames Control of default column names
setEctdColName Control of default column names
setEctdDataMethod Current data storage method
setEctdDateFormat MSToolkit package options
setEctdExternalPath Controls paths to a set of external execution paths
setEctdLogFile MSToolkit package options
setEctdPossibleColNames Control of default column names
setEctdVerbose MSToolkit package options
summarizeTrialMeans Summarize Trial Mean Data
tvDefinition-class tvDefinition class
validNames Check if a character string is a valid R variable name
writeData Write scenario data
writeLogFile Write a job log file